Treponema phagedenis: NCBI 162, [species]

Bovine Digital Dermatitis (BDD): Treponema phagedenis is one of the bacteria implicated in the development of bovine digital dermatitis, a common infectious foot disease affecting cattle. BDD causes painful lesions on the hooves of cattle, leading to lameness and decreased productivity in affected animals. It is considered a significant welfare and economic concern in the dairy industry.
Interdigital Necrobacillosis: Treponema phagedenis has been associated with interdigital necrobacillosis, also known as footrot or foul in the foot, in sheep and goats. This condition is characterized by inflammation, necrosis, and foul-smelling discharge in the interdigital space, leading to lameness and reduced mobility in affected animals.
Swine Necrotic Ear Syndrome (SNES): Treponema phagedenis has been implicated in swine necrotic ear syndrome, a condition characterized by necrotizing inflammation of the ears in pigs. SNES can result in ear necrosis, deformity, and reduced ear mobility, leading to impaired welfare and potential economic losses in pig production.
Human Oral Microbiota: While Treponema phagedenis is primarily associated with diseases in animals, it is also part of the human oral microbiota. In the oral cavity, Treponema species can contribute to dental plaque formation and periodontal diseases if the microbial balance is disrupted. However, the specific role of Treponema phagedenis in oral health and disease in humans is not fully understood and requires further research.

Other Sources for more information:

Immune Epitope Database
The NCBI taxonomy database
UniProt
Immune Epitope Taxonomy Database (IEDB)
AI Engines For more Details: Perplexity Kagi Labs You

Legend

The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
The width of the lines indicates R² (the coefficient of determination)
Green indicates positive slope
Red indicates negative
Interactions are not two way because incidence of each bacteria are different

Treponema phagedenis impacts on other bacteria of the same rank

R²	Slope	Tax Name	Parent Chart
0.2821899950504303	0.6196004152297974	Bifidobacterium eulemuris	Parent Taxa
0.2517177164554596	0.6892338395118713	Anaerobutyricum hallii	Parent Taxa
0.22303506731987	0.6455876231193542	Clostridium sp. M62/1	Parent Taxa
0.21988531947135925	0.6410132646560669	Faecalitalea cylindroides	Parent Taxa
0.21757638454437256	0.6405321955680847	Coprococcus catus	Parent Taxa
0.2163819968700409	0.6165215373039246	[Clostridium] hylemonae	Parent Taxa
0.2083003968000412	0.5927144885063171	Clostridium cadaveris	Parent Taxa
0.2052224576473236	0.5979917049407959	Solibaculum mannosilyticum	Parent Taxa
0.2017686516046524	0.6157433390617371	Dorea formicigenerans	Parent Taxa
0.19769857823848724	0.6037095189094543	Wansuia hejianensis	Parent Taxa
0.196043461561203	0.608279287815094	Anaerostipes hadrus	Parent Taxa
0.19479869306087494	0.6063462495803833	Blautia wexlerae	Parent Taxa
0.194273442029953	0.6054635643959045	Blautia obeum	Parent Taxa
0.1933474987745285	0.5856728553771973	Christensenella minuta	Parent Taxa
0.19285564124584198	0.5987537503242493	Subdoligranulum variabile	Parent Taxa
0.19154269993305206	0.5598284602165222	Blautia liquoris	Parent Taxa
0.18992334604263306	0.5877958536148071	Marvinbryantia formatexigens	Parent Taxa
0.1895180642604828	0.579534113407135	Lachnoclostridium phocaeense	Parent Taxa
0.18939104676246643	0.5977815985679626	Dorea longicatena	Parent Taxa
0.186318039894104	0.540472149848938	Maliibacterium massiliense	Parent Taxa
0.18545320630073547	0.5914748311042786	Coprococcus comes	Parent Taxa
0.18505489826202393	0.5773323774337769	Massilistercora timonensis	Parent Taxa
0.1834057867527008	0.5489752292633057	Lacrimispora saccharolytica	Parent Taxa
0.182604119181633	0.5862727761268616	Blautia sp. SC05B48	Parent Taxa
0.18208053708076477	0.5310413241386414	Parvimonas micra	Parent Taxa
0.17999641597270966	0.5535049438476562	Novisyntrophococcus fermenticellae	Parent Taxa
0.17666658759117126	0.4974273145198822	Clostridium sp. C1	Parent Taxa
0.17042648792266846	0.488177627325058	Komagataeibacter oboediens	Parent Taxa
0.16806192696094513	0.5433414578437805	Clostridium sp. SY8519	Parent Taxa
0.1676238775253296	0.5032498836517334	Lactococcus cremoris	Parent Taxa
0.16713646054267883	0.5399767756462097	Streptococcus suis	Parent Taxa
0.16388724744319916	0.5484604835510254	Faecalibacterium sp. I2-3-92	Parent Taxa
0.1638379842042923	0.5364701747894287	Ligilactobacillus ruminis	Parent Taxa
0.1626242697238922	0.507987916469574	Adlercreutzia hattorii	Parent Taxa
0.15480820834636688	0.5381056666374207	[Ruminococcus] lactaris	Parent Taxa
0.15447324514389038	0.49509337544441223	Acutalibacter muris	Parent Taxa
0.15421906113624573	0.533207356929779	Vescimonas fastidiosa	Parent Taxa
0.15349453687667847	0.4920423924922943	Eubacterium sp. c-25	Parent Taxa
0.15333834290504456	0.4906809628009796	Enterococcus cecorum	Parent Taxa
0.1520688533782959	0.533075213432312	Enterococcus faecium	Parent Taxa
0.15175886452198029	0.5249755382537842	Longicatena caecimuris	Parent Taxa
0.15165430307388306	0.4121913015842438	Phoenicibacter congonensis	Parent Taxa
0.15140341222286224	0.45258158445358276	Treponema peruense	Parent Taxa
0.15089893341064453	0.532658040523529	[Clostridium] scindens	Parent Taxa
0.14831800758838654	0.4744928181171417	Ruminococcus gauvreauii	Parent Taxa
0.1471637487411499	0.4594268500804901	Mageeibacillus indolicus	Parent Taxa
0.14701715111732483	0.3878377676010132	Eggerthella sp. YY7918	Parent Taxa
0.1469162404537201	0.5019761323928833	Qiania dongpingensis	Parent Taxa
0.14665816724300385	0.4159824848175049	Parolsenella massiliensis	Parent Taxa
0.14606161415576935	0.5020685791969299	Lachnoanaerobaculum gingivalis	Parent Taxa
0.14525972306728363	0.4412325620651245	Chordicoccus furentiruminis	Parent Taxa
0.14506351947784424	0.520651638507843	Lawsonibacter asaccharolyticus	Parent Taxa
0.1447530835866928	0.5203360319137573	Intestinimonas butyriciproducens	Parent Taxa
0.14458729326725006	0.4814836084842682	Mogibacterium diversum	Parent Taxa
0.14425818622112274	0.5205602645874023	Anaerotruncus colihominis	Parent Taxa
0.14356385171413422	0.520374596118927	Clostridioides difficile	Parent Taxa
0.14256128668785095	0.5115333795547485	Coprococcus eutactus	Parent Taxa
0.1422463357448578	0.4817512333393097	Catenibacterium sp. co_0103	Parent Taxa
0.14202766120433807	0.49386343359947205	Catenibacterium mitsuokai	Parent Taxa
0.14169147610664368	0.5137921571731567	Faecalibacterium sp. HTF-F	Parent Taxa
0.14078862965106964	0.47927775979042053	Eubacterium limosum	Parent Taxa
0.13715225458145142	0.5086800456047058	[Ruminococcus] torques	Parent Taxa
0.13558068871498108	0.4596460461616516	Turicibacter bilis	Parent Taxa
0.1355685144662857	0.5024330615997314	Faecalibacterium duncaniae	Parent Taxa
0.13546684384346008	0.470803827047348	Ruminococcus champanellensis	Parent Taxa
0.13516120612621307	0.5028008222579956	Coprococcus sp. ART55/1	Parent Taxa
0.13334490358829498	0.5013642907142639	Ruthenibacterium lactatiformans	Parent Taxa
0.13249768316745758	0.4942319989204407	Butyrivibrio crossotus	Parent Taxa
0.13145826756954193	0.49805352091789246	Roseburia hominis	Parent Taxa
0.13137775659561157	0.49623826146125793	Eubacterium ventriosum	Parent Taxa
0.13024143874645233	0.4934523403644562	Faecalibacterium sp. I3-3-89	Parent Taxa
0.1298816055059433	0.3743654489517212	Butyrivibrio fibrisolvens	Parent Taxa
0.1281706839799881	0.36073604226112366	Proteiniclasticum sp. QWL-01	Parent Taxa
0.12485268712043762	0.40685006976127625	Fannyhessea vaginae	Parent Taxa
0.12370071560144424	0.3822965919971466	Allocoprobacillus halotolerans	Parent Taxa
0.12360137701034546	0.4615735113620758	Adlercreutzia equolifaciens	Parent Taxa
0.12338821589946747	0.414725661277771	Pseudobutyrivibrio xylanivorans	Parent Taxa
0.1223040521144867	0.3616463840007782	Parolsenella catena	Parent Taxa
0.12131279706954956	0.452627569437027	Eubacterium callanderi	Parent Taxa
0.12090950459241867	0.36675918102264404	Bacillus paralicheniformis	Parent Taxa
0.11966178566217422	0.37600409984588623	Faecalibaculum rodentium	Parent Taxa
0.11865464597940445	0.4689479470252991	Faecalibacterium sp. IP-3-29	Parent Taxa
0.11853556334972382	0.36334991455078125	Ruminococcus albus	Parent Taxa
0.11833836138248444	0.38840389251708984	Denitrobacterium detoxificans	Parent Taxa
0.11741306632757187	0.4683007597923279	Pusillibacter faecalis	Parent Taxa
0.1171439066529274	0.46924567222595215	Faecalibacterium sp. I4-3-84	Parent Taxa
0.11632367968559265	0.4625859558582306	Sellimonas intestinalis	Parent Taxa
0.11618813127279282	0.46584978699684143	Faecalibacterium sp. I4-1-79	Parent Taxa
0.11461205780506134	0.46300432085990906	Ruminococcus bicirculans (ex Wegman et al. 2014)	Parent Taxa
0.1143818348646164	0.33696603775024414	Berryella intestinalis	Parent Taxa
0.1126299574971199	0.4589827060699463	Vescimonas coprocola	Parent Taxa
0.11181164532899857	0.3329278230667114	Leuconostoc mesenteroides	Parent Taxa
0.11133340746164322	0.3319026827812195	Arabiibacter massiliensis	Parent Taxa
0.11041911691427231	0.4565100073814392	Roseburia intestinalis	Parent Taxa
0.11000292003154755	0.40608760714530945	Gordonibacter urolithinfaciens	Parent Taxa
0.10974376648664474	0.3297888934612274	Cellulosilyticum sp. WCF-2	Parent Taxa
0.10941670089960098	0.4018315374851227	Intestinibaculum porci	Parent Taxa
0.10692258179187775	0.4491104483604431	[Clostridium] innocuum	Parent Taxa
0.10663150995969772	0.43630534410476685	Amedibacterium intestinale	Parent Taxa
0.10636849701404572	0.3530874252319336	Selenomonas sputigena	Parent Taxa
0.10475629568099976	0.3257373571395874	Aminipila luticellarii	Parent Taxa
0.10280803591012955	0.4237474501132965	Eubacterium sp. MSJ-33	Parent Taxa
0.10168136656284332	0.4223891794681549	Flintibacter sp. KGMB00164	Parent Taxa
0.10156364738941193	0.3865326941013336	Ruminococcus bovis	Parent Taxa
0.10139278322458267	0.32134392857551575	Trueperella pyogenes	Parent Taxa

Other bacteria of the same rank impacting Treponema phagedenis

R²	Slope	Tax Name	Parent Chart
0.2517177164554596	0.3652138113975525	Anaerobutyricum hallii	Parent Taxa
0.22303506731987	0.34547606110572815	Clostridium sp. M62/1	Parent Taxa
0.21988531947135925	0.3430277407169342	Faecalitalea cylindroides	Parent Taxa
0.21757638454437256	0.33968064188957214	Coprococcus catus	Parent Taxa
0.2163819968700409	0.35097232460975647	[Clostridium] hylemonae	Parent Taxa
0.2083003968000412	0.3514346182346344	Clostridium cadaveris	Parent Taxa
0.2052224576473236	0.3431861400604248	Solibaculum mannosilyticum	Parent Taxa
0.2017686516046524	0.3276830315589905	Dorea formicigenerans	Parent Taxa
0.19769857823848724	0.3274730145931244	Wansuia hejianensis	Parent Taxa
0.196043461561203	0.32229188084602356	Anaerostipes hadrus	Parent Taxa
0.19479869306087494	0.32126641273498535	Blautia wexlerae	Parent Taxa
0.194273442029953	0.32086730003356934	Blautia obeum	Parent Taxa
0.1933474987745285	0.33012884855270386	Christensenella minuta	Parent Taxa
0.19285564124584198	0.3220950663089752	Subdoligranulum variabile	Parent Taxa
0.19154269993305206	0.34214532375335693	Blautia liquoris	Parent Taxa
0.18992334604263306	0.32311105728149414	Marvinbryantia formatexigens	Parent Taxa
0.1895180642604828	0.32701796293258667	Lachnoclostridium phocaeense	Parent Taxa
0.18939104676246643	0.31682315468788147	Dorea longicatena	Parent Taxa
0.186318039894104	0.34473198652267456	Maliibacterium massiliense	Parent Taxa
0.18545320630073547	0.3135436773300171	Coprococcus comes	Parent Taxa
0.18505489826202393	0.32053443789482117	Massilistercora timonensis	Parent Taxa
0.1834057867527008	0.3340875506401062	Lacrimispora saccharolytica	Parent Taxa
0.182604119181633	0.31146612763404846	Blautia sp. SC05B48	Parent Taxa
0.18208053708076477	0.34287452697753906	Parvimonas micra	Parent Taxa
0.17999641597270966	0.3251938819885254	Novisyntrophococcus fermenticellae	Parent Taxa
0.17666658759117126	0.3551606237888336	Clostridium sp. C1	Parent Taxa
0.17042648792266846	0.3491075336933136	Komagataeibacter oboediens	Parent Taxa
0.16806192696094513	0.30931180715560913	Clostridium sp. SY8519	Parent Taxa
0.1676238775253296	0.33308279514312744	Lactococcus cremoris	Parent Taxa
0.16713646054267883	0.3095252811908722	Streptococcus suis	Parent Taxa
0.16388724744319916	0.29881322383880615	Faecalibacterium sp. I2-3-92	Parent Taxa
0.1638379842042923	0.305400013923645	Ligilactobacillus ruminis	Parent Taxa
0.1626242697238922	0.32013413310050964	Adlercreutzia hattorii	Parent Taxa
0.15480820834636688	0.2876911163330078	[Ruminococcus] lactaris	Parent Taxa
0.15447324514389038	0.3120083212852478	Acutalibacter muris	Parent Taxa
0.15421906113624573	0.28922906517982483	Vescimonas fastidiosa	Parent Taxa
0.15349453687667847	0.3119538724422455	Eubacterium sp. c-25	Parent Taxa
0.15333834290504456	0.31250110268592834	Enterococcus cecorum	Parent Taxa
0.1520688533782959	0.285267174243927	Enterococcus faecium	Parent Taxa
0.15175886452198029	0.2890779674053192	Longicatena caecimuris	Parent Taxa
0.15165430307388306	0.3679221272468567	Phoenicibacter congonensis	Parent Taxa
0.15140341222286224	0.33453288674354553	Treponema peruense	Parent Taxa
0.15089893341064453	0.2832942008972168	[Clostridium] scindens	Parent Taxa
0.14831800758838654	0.31258219480514526	Ruminococcus gauvreauii	Parent Taxa
0.1471637487411499	0.3203203082084656	Mageeibacillus indolicus	Parent Taxa
0.14701715111732483	0.3790687024593353	Eggerthella sp. YY7918	Parent Taxa
0.1469162404537201	0.29267576336860657	Qiania dongpingensis	Parent Taxa
0.14665816724300385	0.3525584936141968	Parolsenella massiliensis	Parent Taxa
0.14606161415576935	0.29091963171958923	Lachnoanaerobaculum gingivalis	Parent Taxa
0.14525972306728363	0.32921352982521057	Chordicoccus furentiruminis	Parent Taxa
0.14506351947784424	0.2786191403865814	Lawsonibacter asaccharolyticus	Parent Taxa
0.1447530835866928	0.27819156646728516	Intestinimonas butyriciproducens	Parent Taxa
0.14458729326725006	0.300295352935791	Mogibacterium diversum	Parent Taxa
0.14425818622112274	0.27712100744247437	Anaerotruncus colihominis	Parent Taxa
0.14356385171413422	0.27588558197021484	Clostridioides difficile	Parent Taxa
0.14256128668785095	0.2786940038204193	Coprococcus eutactus	Parent Taxa
0.1422463357448578	0.295269250869751	Catenibacterium sp. co_0103	Parent Taxa
0.14202766120433807	0.28758490085601807	Catenibacterium mitsuokai	Parent Taxa
0.14169147610664368	0.27577587962150574	Faecalibacterium sp. HTF-F	Parent Taxa
0.14078862965106964	0.29375165700912476	Eubacterium limosum	Parent Taxa
0.13715225458145142	0.2696238160133362	[Ruminococcus] torques	Parent Taxa
0.13558068871498108	0.2949675917625427	Turicibacter bilis	Parent Taxa
0.1355685144662857	0.2698240280151367	Faecalibacterium duncaniae	Parent Taxa
0.13546684384346008	0.2877352237701416	Ruminococcus champanellensis	Parent Taxa
0.13516120612621307	0.26881662011146545	Coprococcus sp. ART55/1	Parent Taxa
0.13334490358829498	0.2659640908241272	Ruthenibacterium lactatiformans	Parent Taxa
0.13249768316745758	0.2680880129337311	Butyrivibrio crossotus	Parent Taxa
0.13145826756954193	0.26394402980804443	Roseburia hominis	Parent Taxa
0.13137775659561157	0.2647473216056824	Eubacterium ventriosum	Parent Taxa
0.13024143874645233	0.2639392614364624	Faecalibacterium sp. I3-3-89	Parent Taxa
0.1298816055059433	0.34693801403045654	Butyrivibrio fibrisolvens	Parent Taxa
0.1281706839799881	0.35530322790145874	Proteiniclasticum sp. QWL-01	Parent Taxa
0.12485268712043762	0.30687642097473145	Fannyhessea vaginae	Parent Taxa
0.12370071560144424	0.32357263565063477	Allocoprobacillus halotolerans	Parent Taxa
0.12360137701034546	0.26778265833854675	Adlercreutzia equolifaciens	Parent Taxa
0.12338821589946747	0.29751768708229065	Pseudobutyrivibrio xylanivorans	Parent Taxa
0.1223040521144867	0.3381868600845337	Parolsenella catena	Parent Taxa
0.12131279706954956	0.26801902055740356	Eubacterium callanderi	Parent Taxa
0.12090950459241867	0.3296700119972229	Bacillus paralicheniformis	Parent Taxa
0.11966178566217422	0.31824594736099243	Faecalibaculum rodentium	Parent Taxa
0.11865464597940445	0.25302305817604065	Faecalibacterium sp. IP-3-29	Parent Taxa
0.11853556334972382	0.3262297809123993	Ruminococcus albus	Parent Taxa
0.11833836138248444	0.30467861890792847	Denitrobacterium detoxificans	Parent Taxa
0.11741306632757187	0.2507214844226837	Pusillibacter faecalis	Parent Taxa
0.1171439066529274	0.249643012881279	Faecalibacterium sp. I4-3-84	Parent Taxa
0.11632367968559265	0.251463919878006	Sellimonas intestinalis	Parent Taxa
0.11618813127279282	0.24941113591194153	Faecalibacterium sp. I4-1-79	Parent Taxa
0.11461205780506134	0.2475399374961853	Ruminococcus bicirculans (ex Wegman et al. 2014)	Parent Taxa
0.1143818348646164	0.33944618701934814	Berryella intestinalis	Parent Taxa
0.1126299574971199	0.2453904151916504	Vescimonas coprocola	Parent Taxa
0.11181164532899857	0.3358435034751892	Leuconostoc mesenteroides	Parent Taxa
0.11133340746164322	0.33543992042541504	Arabiibacter massiliensis	Parent Taxa
0.11041911691427231	0.24187666177749634	Roseburia intestinalis	Parent Taxa
0.11000292003154755	0.2708846926689148	Gordonibacter urolithinfaciens	Parent Taxa
0.10974376648664474	0.3327697515487671	Cellulosilyticum sp. WCF-2	Parent Taxa
0.10941670089960098	0.2722949683666229	Intestinibaculum porci	Parent Taxa
0.10692258179187775	0.2380763590335846	[Clostridium] innocuum	Parent Taxa
0.10663150995969772	0.24439652264118195	Amedibacterium intestinale	Parent Taxa
0.10636849701404572	0.3012525737285614	Selenomonas sputigena	Parent Taxa
0.10475629568099976	0.3215974271297455	Aminipila luticellarii	Parent Taxa
0.10280803591012955	0.24261629581451416	Eubacterium sp. MSJ-33	Parent Taxa
0.10168136656284332	0.24072909355163574	Flintibacter sp. KGMB00164	Parent Taxa
0.10156364738941193	0.2627556622028351	Ruminococcus bovis	Parent Taxa
0.10139278322458267	0.3155272901058197	Trueperella pyogenes	Parent Taxa

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