Roseburia intestinalis: NCBI 166486, [species]

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| DSM 14610| NCIMB 13810| Roseburia intestinalis| Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006| strain L1-82

1. Butyrate Production: Roseburia intestinalis is an important butyrate producer. Butyrate, a short-chain fatty acid, serves as a vital energy source for the cells lining the colon (colonocytes) and contributes to maintaining gut barrier function and supporting a healthy gut environment.

2. Gut Health and Integrity: Butyrate produced by Roseburia intestinalis and other butyrate-producing bacteria plays a crucial role in promoting gut health. It helps nourish the cells lining the colon, stimulates mucus production, regulates the inflammatory response in the gut, and supports the maintenance of a healthy gut barrier.

3. Anti-inflammatory Properties: Butyrate has been shown to exhibit anti-inflammatory effects in the gut. By modulating immune responses and reducing the production of pro-inflammatory molecules, butyrate contributes to maintaining immune balance and mitigating inflammation in the gut.

4. Metabolic Health: Some studies suggest a potential link between Roseburia intestinalis and metabolic health. Higher abundance or activity of butyrate-producing bacteria like Roseburia intestinalis has been associated with improved metabolic parameters, such as glucose metabolism and insulin sensitivity.

5. Association with Dietary Fiber: Roseburia intestinalis thrives on dietary fibers that escape digestion in the small intestine. Consuming a diet rich in fiber and prebiotics supports the growth and activity of beneficial bacteria like Roseburia intestinalis.

6. Links to Gut Dysbiosis and Diseases: Alterations in the abundance or diversity of Roseburia intestinalis and other butyrate-producing bacteria have been observed in various conditions, including inflammatory bowel diseases (IBD), obesity, and metabolic disorders. However, the causal relationship and specific roles in disease development are still under investigation.

7. Potential Therapeutic Role: Some research suggests that interventions aimed at enhancing the abundance or activity of Roseburia intestinalis and other butyrate-producing bacteria might have therapeutic potential for improving gut health and managing certain digestive disorders.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Roseburia intestinalis impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.7119227051734924	0.804877519607544	Roseburia rectibacter	Parent Taxa
0.5330702066421509	0.6957326531410217	Butyrivibrio crossotus	Parent Taxa
0.4796587824821472	0.6901761889457703	Roseburia hominis	Parent Taxa
0.43322139978408813	0.6970116496086121	Cloacibacterium caeni	Parent Taxa
0.4310489892959595	0.6511738896369934	Coprococcus catus	Parent Taxa
0.42414650321006775	0.6404165625572205	Lachnospira eligens	Parent Taxa
0.42270517349243164	0.6444912552833557	Simiaoa sunii	Parent Taxa
0.4152897000312805	0.640676736831665	Coprococcus comes	Parent Taxa
0.41385525465011597	0.6229862570762634	Clostridium sp. M62/1	Parent Taxa
0.40622469782829285	0.6343526244163513	Dorea longicatena	Parent Taxa
0.3959023356437683	0.5738697648048401	Ligilactobacillus ruminis	Parent Taxa
0.39408573508262634	0.6127430200576782	Eubacterium ventriosum	Parent Taxa
0.39042890071868896	0.6085433959960938	Coprococcus sp. ART55/1	Parent Taxa
0.38467344641685486	0.5998562574386597	Faecalibacterium duncaniae	Parent Taxa
0.3801879286766052	0.5987667441368103	Faecalibacterium sp. I3-3-89	Parent Taxa
0.3775802552700043	0.6122584342956543	Blautia obeum	Parent Taxa
0.3758813440799713	0.6023783087730408	Faecalibacterium sp. I4-3-84	Parent Taxa
0.3755093514919281	0.5936754941940308	[Ruminococcus] lactaris	Parent Taxa
0.3725317716598511	0.60935378074646	Anaerobutyricum hallii	Parent Taxa
0.3644895553588867	0.5908803343772888	Dorea formicigenerans	Parent Taxa
0.3606017231941223	0.6006349921226501	Anaerostipes hadrus	Parent Taxa
0.3603196442127228	0.5812445878982544	Faecalibacterium sp. HTF-F	Parent Taxa
0.3596752882003784	0.582686185836792	Faecalibacterium sp. I4-1-79	Parent Taxa
0.3559565842151642	-0.6495557427406311	Staphylococcus epidermidis	Parent Taxa
0.34921199083328247	0.5676730275154114	Faecalibacterium sp. IP-3-29	Parent Taxa
0.3490939438343048	0.5882733464241028	[Ruminococcus] torques	Parent Taxa
0.3490760922431946	0.561899721622467	Coprococcus eutactus	Parent Taxa
0.344983845949173	0.5669950246810913	Subdoligranulum variabile	Parent Taxa
0.3331338167190552	0.5773072242736816	Blautia wexlerae	Parent Taxa
0.3324964940547943	0.5232194662094116	Clostridium sp. SY8519	Parent Taxa
0.33111372590065	0.5419743657112122	Pectobacterium carotovorum	Parent Taxa
0.3303734064102173	0.5497117638587952	Faecalibacterium sp. I2-3-92	Parent Taxa
0.3281114101409912	0.5638887882232666	Blautia sp. SC05B48	Parent Taxa
0.32785189151763916	0.5467800498008728	Wansuia hejianensis	Parent Taxa
0.3268931806087494	0.5728845596313477	Faecalibacterium prausnitzii	Parent Taxa
0.3248010575771332	0.5395938754081726	Wujia chipingensis	Parent Taxa
0.32329443097114563	0.5915789604187012	Bifidobacterium eulemuris	Parent Taxa
0.31346338987350464	0.616188108921051	Pantoea sp. At-9b	Parent Taxa
0.3071494996547699	0.5423069000244141	Ruminococcus bicirculans (ex Wegman et al. 2014)	Parent Taxa
0.3001944124698639	0.5059114694595337	Massilistercora timonensis	Parent Taxa
0.2879714369773865	0.43467068672180176	Pseudomonas protegens	Parent Taxa
0.28222668170928955	0.5056765079498291	Faecalibacterium sp. IP-1-18	Parent Taxa
0.28177008032798767	0.42254334688186646	Pseudobutyrivibrio xylanivorans	Parent Taxa
0.2647309899330139	0.4834316074848175	Faecalibacterium sp. I3-3-33	Parent Taxa
0.26464423537254333	0.5042279958724976	Anaerotruncus colihominis	Parent Taxa
0.2622191607952118	0.49555036425590515	Faecalibacillus intestinalis	Parent Taxa
0.26103392243385315	0.4980466961860657	Faecalitalea cylindroides	Parent Taxa
0.2609148919582367	0.48174211382865906	Longicatena caecimuris	Parent Taxa
0.2569122612476349	0.47704222798347473	Globicatella sanguinis	Parent Taxa

Other bacteria of the same rank impacting Roseburia intestinalis

R2	Slope	Tax Name	Parent Chart
0.7481731176376343	0.9082867503166199	Roseburia rectibacter	Parent Taxa
0.5927261710166931	0.8120551705360413	Butyrivibrio crossotus	Parent Taxa
0.5186757445335388	0.7855401635169983	Ligilactobacillus ruminis	Parent Taxa
0.4993140697479248	0.8124767541885376	Pseudobutyrivibrio xylanivorans	Parent Taxa
0.4845455586910248	0.6989229321479797	Roseburia hominis	Parent Taxa
0.4694969952106476	0.7471752762794495	Clostridium sp. SY8519	Parent Taxa
0.4612342119216919	0.7036585807800293	Clostridium sp. M62/1	Parent Taxa
0.44802188873291016	0.6816731691360474	Lachnospira eligens	Parent Taxa
0.4434715211391449	0.672477662563324	Coprococcus catus	Parent Taxa
0.4372570514678955	0.689009964466095	Faecalibacterium duncaniae	Parent Taxa
0.43657857179641724	0.6681248545646667	Simiaoa sunii	Parent Taxa
0.433959424495697	0.6814060807228088	Coprococcus sp. ART55/1	Parent Taxa
0.4331420958042145	0.6782690286636353	Eubacterium ventriosum	Parent Taxa
0.42984601855278015	0.6945330500602722	Coprococcus eutactus	Parent Taxa
0.4266059398651123	0.6761693954467773	Faecalibacterium sp. I3-3-89	Parent Taxa
0.42433521151542664	0.6560720801353455	Coprococcus comes	Parent Taxa
0.4230498671531677	0.6727854609489441	[Ruminococcus] lactaris	Parent Taxa
0.4164851903915405	0.693810224533081	Massilistercora timonensis	Parent Taxa
0.41513505578041077	0.6863478422164917	Wujia chipingensis	Parent Taxa
0.4146408140659332	0.6751457452774048	Faecalibacterium sp. IP-3-29	Parent Taxa
0.4145749807357788	0.6705570220947266	Faecalibacterium sp. HTF-F	Parent Taxa
0.4130740463733673	0.6460025310516357	Dorea longicatena	Parent Taxa
0.4097605347633362	0.6781309843063354	Faecalibacterium sp. I2-3-92	Parent Taxa
0.40810659527778625	0.6624372005462646	Faecalibacterium sp. I4-1-79	Parent Taxa
0.40729960799217224	0.7133392095565796	Lacrimispora saccharolytica	Parent Taxa
0.4054793119430542	0.6513625979423523	Faecalibacterium sp. I4-3-84	Parent Taxa
0.40355047583580017	0.670051097869873	Wansuia hejianensis	Parent Taxa
0.4032217860221863	0.6632392406463623	Subdoligranulum variabile	Parent Taxa
0.3987329602241516	0.7214286923408508	Intestinibaculum porci	Parent Taxa
0.3974776864051819	0.6454629898071289	Dorea formicigenerans	Parent Taxa
0.3894837498664856	0.6823910474777222	Eubacterium sp. MSJ-33	Parent Taxa
0.38441187143325806	0.6760907769203186	[Clostridium] hylemonae	Parent Taxa
0.38304805755615234	0.6213674545288086	Blautia obeum	Parent Taxa
0.3753789961338043	0.614105224609375	Anaerobutyricum hallii	Parent Taxa
0.3681616485118866	0.6547499299049377	Blautia pseudococcoides	Parent Taxa
0.36404454708099365	0.6387118697166443	Faecalibacterium sp. IP-1-18	Parent Taxa
0.36230963468551636	0.6407586336135864	Faecalibacterium sp. I3-3-33	Parent Taxa
0.36049386858940125	0.6004276871681213	Anaerostipes hadrus	Parent Taxa
0.35907021164894104	0.6404702067375183	Longicatena caecimuris	Parent Taxa
0.35840514302253723	0.6596729755401611	Qiania dongpingensis	Parent Taxa
0.35689181089401245	0.6011187434196472	[Ruminococcus] torques	Parent Taxa
0.35362741351127625	0.6055594682693481	Blautia sp. SC05B48	Parent Taxa
0.3502378761768341	0.6123417615890503	Ruminococcus bicirculans (ex Wegman et al. 2014)	Parent Taxa
0.34891456365585327	0.6492588520050049	Lachnoanaerobaculum gingivalis	Parent Taxa
0.3397161066532135	0.669986367225647	Komagataeibacter oboediens	Parent Taxa
0.3359313905239105	0.6459746956825256	Romboutsia ilealis	Parent Taxa
0.3330858647823334	0.5772180557250977	Blautia wexlerae	Parent Taxa
0.32838955521583557	0.6412853598594666	Blautia liquoris	Parent Taxa
0.3267998993396759	0.6298291087150574	Catenibacterium mitsuokai	Parent Taxa
0.32523441314697266	0.6386950612068176	Catenibacterium sp. co_0103	Parent Taxa
0.3240705132484436	0.5682581067085266	Faecalibacterium prausnitzii	Parent Taxa
0.3239113688468933	0.6003201007843018	Vescimonas fastidiosa	Parent Taxa
0.3215043842792511	0.6052435040473938	Marvinbryantia formatexigens	Parent Taxa
0.31868353486061096	0.5868743062019348	Faecalibacillus intestinalis	Parent Taxa
0.3099650740623474	0.5769397020339966	Faecalitalea cylindroides	Parent Taxa
0.30773043632507324	0.6130359172821045	Novisyntrophococcus fermenticellae	Parent Taxa
0.3066316545009613	0.6300652623176575	Romboutsia sp. 13368	Parent Taxa
0.30213475227355957	0.6094154715538025	Clostridium cadaveris	Parent Taxa
0.2990809977054596	0.5603942275047302	Anaerotruncus colihominis	Parent Taxa
0.29509714245796204	0.6144329905509949	Enterococcus cecorum	Parent Taxa
0.2917611598968506	0.5893307328224182	Flintibacter sp. KGMB00164	Parent Taxa
0.29027608036994934	0.5845165848731995	Christensenella minuta	Parent Taxa
0.2886941432952881	0.6145350337028503	Ruminococcus bovis	Parent Taxa
0.288507342338562	0.556525468826294	Lawsonibacter asaccharolyticus	Parent Taxa
0.28753405809402466	0.6178818941116333	Treponema peruense	Parent Taxa
0.2875058948993683	0.600359320640564	Ruminococcus champanellensis	Parent Taxa
0.2837525010108948	0.5510034561157227	Vescimonas coprocola	Parent Taxa
0.276954710483551	0.5957513451576233	Turicibacter bilis	Parent Taxa
0.2769380807876587	0.5986244678497314	Ruminococcus gauvreauii	Parent Taxa
0.2698797881603241	0.5386930704116821	Pusillibacter faecalis	Parent Taxa
0.26663631200790405	0.5889205932617188	Romboutsia sp. CE17	Parent Taxa
0.26607853174209595	0.5760931968688965	Monoglobus pectinilyticus	Parent Taxa
0.26430755853652954	0.5446157455444336	Oscillibacter hominis	Parent Taxa
0.26240435242652893	0.5298670530319214	Intestinimonas butyriciproducens	Parent Taxa
0.2623860538005829	0.5560462474822998	Lachnoclostridium phocaeense	Parent Taxa
0.2597881853580475	0.5579116940498352	Solibaculum mannosilyticum	Parent Taxa
0.25556933879852295	-0.5683726668357849	Staphylococcus epidermidis	Parent Taxa
0.25525543093681335	0.5097665190696716	Clostridioides difficile	Parent Taxa
0.25289013981819153	0.5685707926750183	Maliibacterium massiliense	Parent Taxa