Lawsonia Details: NCBI 41707, gram-negative or unknown [genus]

| Lawsonia| Lawsonia McOrist et al. 1995

1. Animal Pathogen:

   • Lawsonia intracellularis is primarily considered a veterinary pathogen. It causes a disease known as proliferative enteropathy in animals, particularly in swine (pigs) and horses.

2. Proliferative Enteropathy:

   • In affected animals, Lawsonia intracellularis is associated with proliferative enteropathy, which is characterized by thickening of the intestinal mucosa and can lead to clinical signs such as diarrhea, weight loss, and reduced growth.

3. Transmission in Animals:

   • Transmission of Lawsonia intracellularis among animals typically occurs through the fecal-oral route. Contaminated water, feed, or fomites can contribute to the spread of the bacterium within animal populations.

4. Zoonotic Potential:

   • Lawsonia intracellularis is generally not considered a zoonotic pathogen, meaning it is not known to cause disease in humans. The primary concern is related to its impact on animal health and the agricultural industry.

5. Impacts on Animal Production:

   • In agricultural settings, Lawsonia intracellularis infections in swine can have economic implications due to reduced growth rates and increased mortality rates in affected animals. Control measures may include vaccination and management practices.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Lawsonia

• Lab Low and High are calculated using the formula that most labs use: Mean - 1.95 Standard Deviation to Mean + 1.95 Standard Deviation

These are values that are computed from lab specific samples and are in percentage

Lab	Frequency	Average	Median	Minimum	Maximum	Std.Dev.	Skew	25 - 75 Percentile	5 - 95 Percentile	Lab Ranges	Box-Plot-Whiskers	Harmonic Mean	Geometric Mean	Obs.
BiomeSight	0.0084	0.0018	0.002	0.001	0.004	0.0007	-0.8256	0.001 - 0.002	0.001 - 0.003	0.0004 - 0.0032	-0.0005 - 0.0035	0.0016	0.0017	31
Thorne	0.328	0.0002	0.0002	0.0001	0.0008	0.0002	0.5088	0.0001 - 0.0003	0.0001 - 0.0007	-0.0001 - 0.0006	-0.0002 - 0.0006	0.0002	0.0002	62
Thryve	0.4798	0.0176	0.0056	0.0001	4.4852	0.1843	0.196	0.0028 - 0.0109	0.0013 - 0.0317	-0.3418 - 0.3771	-0.0093 - 0.0231	0.0031	0.0058	595

External Reference Ranges for Lawsonia

Lawsonia (NCBI 41707) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
Metagenomics	0	5000	0	0.5
PrecisionBiome	2.1405869119917043E-05	0.0008273515850305557	0	0

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Amino Acid and similar	Epicatechin {Green tea polyphenol}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Amino Acid and similar	N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide {Melatonin}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Amino Acid and similar	Trichosanic acid {pomegranate seed oil}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	azithromycin,[CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	doxycycline [CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	florfenicol	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	minocycline [CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Common and OTC Supplements	3,3',4',5,7-pentahydroxyflavone {Quercetin}	3 Studies recorded. The consensus is Decreases📓, Click for details.
Common and OTC Supplements	5-Hydroxytryptophan {5-HTP}	1 Studies recorded. The consensus is Increases📓, Click for details.
Common and OTC Supplements	Tributyrin	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	dietary fiber	9 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	Fiber, total dietary	8 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	high-fat diets	4 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	High-fibre diet {Whole food diet}	8 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	High-protein diet {Atkins low-carbohydrate diet}	2 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	high-saturated fat diet	2 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	hypocaloric hyperproteic diet	2 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	ketogenic diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	Pisum sativum {pea}	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	Slow digestible carbohydrates. {Low Glycemic}	11 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	Traditional Mediterranean diet {Mediterranean diet}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	whole-grain diet	4 Studies recorded. The consensus is Decreases📓, Click for details.
Drug or "Non-drug"	florfenicol	1 Studies recorded. The consensus is Decreases📓, Click for details.
Drug or "Non-drug"	nsaid	1 Studies recorded. The consensus is Increases📓, Click for details.
Flavonoids, Polyphenols etc	2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one {Luteolin}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Flavonoids, Polyphenols etc	5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one {Apigenin }	1 Studies recorded. The consensus is Increases📓, Click for details.
Flavonoids, Polyphenols etc	Grape Polyphenols {Grape Flavonoids}	4 Studies recorded. The consensus is Decreases📓, Click for details.
Flavonoids, Polyphenols etc	Humulus lupulus compound {Xanthohumol}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Flavonoids, Polyphenols etc	polyphenols	4 Studies recorded. The consensus is Decreases📓, Click for details.
Flavonoids, Polyphenols etc	Pyroguaiac acid {Guaiacol}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Flavonoids, Polyphenols etc	quebracho	1 Studies recorded. The consensus is Decreases📓, Click for details.
Flavonoids, Polyphenols etc	resveratrol-pterostilbene x Quercetin {quercetin x resveratrol}	4 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	A2 variant of beta-casein {A2 Milk}	3 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Actinidia deliciosa/chinensis {kiwifruit}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Adeps suillus {Lard}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Avena sativa x Hordeum vulgare {barley,oat}	4 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Bovine Milk Products {Dairy}	6 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Caffeine	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Coffee	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Cola aspartame {Diet Cola}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Euphausia superba {Krill Oil}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	fruit	8 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	fruit/legume fibre	8 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Ganoderma sichuanense {Reishi Mushroom}	2 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	grapes	4 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	green tea	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	henopodium quinoa {Quinoa}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Hericium erinaceus {Lion's Mane Mushroom }	2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	high red meat	2 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Hordeum vulgare {Barley}	4 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Humulus lupulus {Hops}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Hydrastis canadensis {Goldenseal}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	olive oil {olive oil}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	oolong teas	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Orange Juice	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	pectin {pectin}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Punica granatum {pomegranate}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Rubus {Raspberries}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	tea	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Vaccinium vitis-idaea {lingonberries}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	vegetarians	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Whole Cow milk {Whole Milk}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	yogurt	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine}	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	allium sativum {garlic}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Azadirachta indica {Neem}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	Camellia Linnaeus {camellia}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Chamaemelum nobile {Camomile}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Morinda citrifolia {Noni}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Pulvis ledebouriellae compositae {Bofutsushosan}	1 Studies recorded. The consensus is Increases📓, Click for details.
Miscellaneous, food additives, and other odd items	cholic,taurocholic ,chenodeoxycholic,glycocholic acids {Bile supplements}	2 Studies recorded. The consensus is Increases📓, Click for details.
Miscellaneous, food additives, and other odd items	ß-sitosterol {beta-sitosterol}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	(2->1)-beta-D-fructofuranan {Inulin}	4 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	arabinogalactan {arabinogalactan}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	Cichorium intybus {Chicory}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	Human milk oligosaccharides (prebiotic, Holigos, Stachyose)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	oligosaccharides {oligosaccharides}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	ß-glucan {Beta-Glucan}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prescription - Other	proton-pump inhibitors (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus subtilis {B.Subtilis }	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus subtilis,lactobacillus acidophilus	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus,lactobacillus,streptococcus,saccharomyces probiotic	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium	2 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	Bifidobacterium animalis {B. animalis}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	Bifidobacterium animalis subsp. lactis {B. Lactis}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium bifidum {B. bifidum}	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium lactis,streptococcus thermophilus probiotic	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium pseudocatenulatum {B. pseudocatenulatum }	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium pseudocatenulatum li09,bifidobacterium catenulatum li10	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	Clostridium butyricum MIYAIRI 588 {Miyarisan}	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	Lacticaseibacillus rhamnosus {l. rhamnosus}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus paracasei,lactobacillus acidophilus,bifidobacterium animalis	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	Lactobacillus plantarum {L. plantarum}	6 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus rhamnosus gg	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus rhamnosus gg,bifidobacterium animalis lactis ,lactobacillus paracasei {cvs maximum strength probiotic}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	Lentilactobacillus kefiri {Kefibios}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Sugar and similar	synthetic disaccharide derivative of lactose {Lactulose}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Vitamins, Minerals and similar	Potassium iodide {Iodine Supplement}	1 Studies recorded. The consensus is Increases📓, Click for details.