Faecalibacterium prausnitzii: NCBI 853, [species]

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| "Bacillus mucosus anaerobius" Prausnitz 1922| "Bacteroides praussnitzii" (sic) Hauduroy et al. 1937| ATCC 27768| Bacillus mucosus anaerobius| Bacteroides praussnitzii| butyrate-producing bacterium A2-165| Faecalibacterium prausnitzii| Faecalibacterium prausnitzii (Hauduroy et al. 1937) Duncan et al. 2002| Fusobacterium prausnitzii| Fusobacterium prausnitzii (Hauduroy et al. 1937) Moore and Holdeman 1970 (Approved Lists 1980)| NCIMB 13872

1. Butyrate Production: Faecalibacterium prausnitzii is known for its ability to produce butyrate, a short-chain fatty acid (SCFA). Butyrate serves as a vital energy source for the cells lining the colon, contributing to their health and integrity. It has anti-inflammatory properties and helps maintain gut barrier function.

2. Anti-inflammatory Effects: Butyrate produced by Faecalibacterium prausnitzii has potent anti-inflammatory properties that can help modulate the immune response in the gut. It can regulate the production of inflammatory molecules, potentially reducing gut inflammation and contributing to the management of inflammatory conditions like inflammatory bowel diseases (IBD).

3. Gut Health: Faecalibacterium prausnitzii plays a role in promoting overall gut health by contributing to the maintenance of a balanced gut microbiota. Its abundance in the gut has been associated with a healthier gut environment, potentially reducing the risk of gastrointestinal disorders and supporting gut barrier function.

4. Immune Modulation: This bacterium has been suggested to have immunomodulatory effects, influencing the immune system's function beyond the gut. It may contribute to a balanced immune response and could have implications in managing immune-related conditions.

5. Metabolic Health: Some research suggests that Faecalibacterium prausnitzii abundance might be associated with improved metabolic health. Higher levels of this bacterium have been correlated with better glucose metabolism and lower levels of markers related to metabolic disorders, such as insulin resistance.

6. Disease Associations: Alterations in the abundance of Faecalibacterium prausnitzii have been observed in various diseases, including inflammatory bowel diseases (IBD), irritable bowel syndrome (IBS), and metabolic disorders. However, its exact role in these conditions and whether the changes observed are causal or consequential remain areas of ongoing research.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Faecalibacterium prausnitzii impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.5924996733665466	0.721284031867981	Faecalibacterium sp. I3-3-33	Parent Taxa
0.55318284034729	0.7285923957824707	Faecalibacterium sp. I4-3-84	Parent Taxa
0.5527085661888123	0.8033757209777832	Cloacibacterium caeni	Parent Taxa
0.534534752368927	0.7078951597213745	Faecalibacterium sp. I3-3-89	Parent Taxa
0.5191859006881714	0.6886362433433533	Faecalibacterium sp. IP-3-29	Parent Taxa
0.48901787400245667	0.6767305731773376	Faecalibacterium sp. I4-1-79	Parent Taxa
0.4625040888786316	0.6436924934387207	Faecalibacterium sp. IP-1-18	Parent Taxa
0.43738606572151184	0.6385457515716553	Faecalibacterium sp. HTF-F	Parent Taxa
0.42599478363990784	0.6295456290245056	Faecalibacterium duncaniae	Parent Taxa
0.42170780897140503	0.6158181428909302	Faecalibacterium sp. I2-3-92	Parent Taxa
0.3721507489681244	0.6054040193557739	Proteiniphilum saccharofermentans	Parent Taxa
0.36603018641471863	0.661900520324707	Aeromonas veronii	Parent Taxa
0.35307592153549194	0.5880888104438782	Simiaoa sunii	Parent Taxa
0.35248899459838867	0.5905343890190125	Roseburia hominis	Parent Taxa
0.3304225206375122	0.5648483037948608	Lachnospira eligens	Parent Taxa
0.3240705132484436	0.5682581067085266	Roseburia intestinalis	Parent Taxa
0.30173927545547485	0.4380072355270386	Skunavirus fd13	Parent Taxa
0.28561607003211975	0.5120700001716614	Roseburia rectibacter	Parent Taxa
0.28213605284690857	-0.5544715523719788	Staphylococcus epidermidis	Parent Taxa
0.2779453694820404	0.5120885968208313	Vescimonas coprocola	Parent Taxa
0.27130401134490967	0.5023399591445923	Subdoligranulum variabile	Parent Taxa
0.27066758275032043	0.49642714858055115	Butyrivibrio crossotus	Parent Taxa
0.26423293352127075	0.5066807270050049	Dysosmobacter welbionis	Parent Taxa
0.25778862833976746	0.49565860629081726	Eubacterium ventriosum	Parent Taxa
0.25586920976638794	0.49093544483184814	[Ruminococcus] lactaris	Parent Taxa

Other bacteria of the same rank impacting Faecalibacterium prausnitzii

R2	Slope	Tax Name	Parent Chart
0.6587385535240173	0.8650826215744019	Faecalibacterium sp. I3-3-33	Parent Taxa
0.5787322521209717	0.7795031666755676	Faecalibacterium sp. I4-3-84	Parent Taxa
0.575667679309845	0.7966554760932922	Faecalibacterium sp. IP-3-29	Parent Taxa
0.5749806761741638	0.7862414717674255	Faecalibacterium sp. I3-3-89	Parent Taxa
0.536802351474762	0.7766219973564148	Faecalibacterium sp. IP-1-18	Parent Taxa
0.5337846279144287	0.7587869167327881	Faecalibacterium sp. I4-1-79	Parent Taxa
0.4996473789215088	0.7497904896736145	Faecalibacterium sp. I2-3-92	Parent Taxa
0.4897020757198334	0.7296860218048096	Faecalibacterium sp. HTF-F	Parent Taxa
0.48012661933898926	0.7230852246284485	Faecalibacterium duncaniae	Parent Taxa
0.36989539861679077	0.6158850193023682	Simiaoa sunii	Parent Taxa
0.3607672154903412	0.6041966080665588	Roseburia hominis	Parent Taxa
0.35851094126701355	0.6108037829399109	Lachnospira eligens	Parent Taxa
0.35848167538642883	0.6296089291572571	Roseburia rectibacter	Parent Taxa
0.3520554006099701	0.6479945778846741	Flintibacter sp. KGMB00164	Parent Taxa
0.35150083899497986	0.6262022852897644	Butyrivibrio crossotus	Parent Taxa
0.34439903497695923	0.6638458371162415	Campylobacter coli	Parent Taxa
0.33538365364074707	0.6057589054107666	Subdoligranulum variabile	Parent Taxa
0.328429251909256	0.5937373638153076	Vescimonas coprocola	Parent Taxa
0.3268931806087494	0.5728845596313477	Roseburia intestinalis	Parent Taxa
0.31963080167770386	0.6029995679855347	Wujia chipingensis	Parent Taxa
0.31272104382514954	0.6438182592391968	Butyricicoccus sp. GAM44	Parent Taxa
0.3101452589035034	0.5882116556167603	Vescimonas fastidiosa	Parent Taxa
0.3071573078632355	0.5741860866546631	[Ruminococcus] lactaris	Parent Taxa
0.30629661679267883	0.6057157516479492	Eubacterium sp. MSJ-33	Parent Taxa
0.3045709431171417	0.5853989124298096	Coprococcus eutactus	Parent Taxa
0.30101361870765686	0.5660553574562073	Eubacterium ventriosum	Parent Taxa
0.29788830876350403	0.5654569864273071	Coprococcus sp. ART55/1	Parent Taxa
0.29008591175079346	-0.6065176725387573	Staphylococcus epidermidis	Parent Taxa
0.2891118824481964	0.5703474879264832	Oscillibacter hominis	Parent Taxa
0.2870279550552368	0.5440454483032227	Dysosmobacter welbionis	Parent Taxa
0.2850838005542755	0.5475764870643616	Dorea formicigenerans	Parent Taxa
0.2828250229358673	0.6116807460784912	Campylobacter jejuni	Parent Taxa
0.2827910780906677	0.5804466605186462	Clostridium sp. SY8519	Parent Taxa
0.2762164771556854	0.5736594200134277	Ligilactobacillus ruminis	Parent Taxa
0.2758754789829254	0.5869999527931213	Monoglobus pectinilyticus	Parent Taxa
0.27318039536476135	0.5414990186691284	Ruminococcus bicirculans (ex Wegman et al. 2014)	Parent Taxa
0.2693326473236084	0.5385534763336182	Clostridium sp. M62/1	Parent Taxa
0.2672203481197357	0.5306071639060974	Anaerotruncus colihominis	Parent Taxa
0.2653942108154297	0.5363248586654663	Faecalibacillus intestinalis	Parent Taxa
0.2647686004638672	0.5330967903137207	Intestinimonas butyriciproducens	Parent Taxa
0.254275381565094	0.5232833623886108	Lawsonibacter asaccharolyticus	Parent Taxa
0.2517903447151184	0.5366227030754089	[Eubacterium] hominis	Parent Taxa
0.2511206269264221	0.5292893648147583	Wansuia hejianensis	Parent Taxa
0.25103020668029785	0.5049702525138855	[Ruminococcus] torques	Parent Taxa