Verrucomicrobiota Details: NCBI 74201, gram-negative or unknown [phylum]

| Verrucomicrobaeota| Verrucomicrobaeota Oren et al. 2015| Verrucomicrobia| Verrucomicrobia (Hedlund et al. 1997) Yoon et al. 2010| Verrucomicrobia Hedlund 2012| Verrucomicrobiota

1. Mucosal Surfaces:

   • Verrucomicrobia bacteria are often found in mucosal surfaces, including the gastrointestinal tract. Their presence in the mucosal environment suggests potential interactions with the host's immune system and other microorganisms in these regions.

2. Akkermansia muciniphila:

   • One of the well-studied genera within Verrucomicrobia is Akkermansia. Akkermansia muciniphila is a species known to inhabit the mucus layer of the intestinal lining. Research has suggested that A. muciniphila may have positive effects on metabolic health, including its potential role in maintaining mucosal integrity and modulating metabolic pathways.

3. Mucus Degradation:

   • Some members of Verrucomicrobia, including Akkermansia species, are specialized in utilizing mucin, a component of the protective mucus layer in the gut. This ability to degrade mucin may influence the gut environment and the interactions between the microbiota and the host.

4. Metabolic Health:

   • Akkermansia muciniphila has been associated with metabolic health benefits in preclinical studies. It has been linked to improvements in glucose metabolism, insulin sensitivity, and lipid metabolism. However, the translation of these findings to human health is an area of ongoing investigation.

5. Immunomodulation:

   • Verrucomicrobia bacteria may play a role in immunomodulation, influencing the host's immune response. The interactions between Verrucomicrobia and the immune system are complex and context-dependent.

6. Associations with Disease:

   • Altered abundances of Verrucomicrobia have been observed in studies of the gut microbiota in various health conditions. Changes in the relative abundance of Verrucomicrobia, including increases or decreases, have been reported in conditions such as inflammatory bowel disease (IBD), obesity, and diabetes. However, the specific contributions of Verrucomicrobia to these conditions are still being explored.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Verrucomicrobiota

• Lab Low and High are calculated using the formula that most labs use: Mean - 1.95 Standard Deviation to Mean + 1.95 Standard Deviation

These are values that are computed from lab specific samples and are in percentage

Lab	Frequency	Average	Median	Minimum	Maximum	Std.Dev.	Skew	25 - 75 Percentile	5 - 95 Percentile	Lab Ranges	Box-Plot-Whiskers	Harmonic Mean	Geometric Mean	Obs.
AmericanGut	0.6667	0.9996	0.5304	0.0102	2.8263	1.0713	1.3137	0.095 - 1.6986	0.0408 - 2.6457	-1.0894 - 3.0885	-2.3104 - 4.1041	0.0725	0.3581	10
BiomeSight	0.9309	1.5134	0.044	0.001	100	4.8141	0.9157	0.007 - 0.873	0.002 - 8.0873	-7.8741 - 10.9009	-1.292 - 2.172	0.0097	0.077	3449
BiomeSightRdp	0.7778	0.6388	0.004	0.001	6.669	1.6028	1.1882	0.002 - 0.245	0.001 - 3.112	-2.4867 - 3.7643	-0.3625 - 0.6095	0.0036	0.0198	21
CosmosId	0.5714	0.2167	0.0815	0.001	1.11	0.2939	1.3801	0.0047 - 0.3508	0.001 - 0.731	-0.3564 - 0.7898	-0.5142 - 0.8698	0.005	0.0445	20
custom	0.4468	1.5495	0.533	0.0001	7.21	2.1403	1.4248	0.0054 - 2.559	0.0001 - 5.397	-2.6241 - 5.7231	-3.825 - 6.3894	0.001	0.1106	21
es-xenogene	0.9545	0.3966	0.05	0.003	3.184	0.8555	1.2155	0.013 - 0.16	0.004 - 2.546	-1.2716 - 2.0649	-0.2075 - 0.3805	0.018	0.0654	21
Microba	0.36	2.0736	0.36	0.039	16.1	5.2679	0.9759	0.044 - 0.5952	0.041 - 10.0224	-8.1989 - 12.3461	-0.7828 - 1.422	0.1061	0.2947	9
SequentiaBiotech	0.7778	3.444	2.7143	0.0337	21.8453	4.4319	0.494	0.2202 - 4.6793	0.0441 - 9.3667	-5.1982 - 12.0862	-6.4685 - 11.368	0.224	1.2021	28
Thorne	0.9577	0.1937	0.0097	0.0001	5.4644	0.6053	0.9122	0.0042 - 0.0776	0.0021 - 0.8185	-0.9866 - 1.3741	-0.1059 - 0.1877	0.0032	0.0195	181
Thryve	0.8613	1.5844	0.0792	0.0001	50.8612	4.3772	1.0316	0.008 - 1.1703	0.002 - 8.3006	-6.9513 - 10.12	-1.7354 - 2.9137	0.008	0.0984	1068
uBiome	0.6413	4.6012	1.3714	0.002	79.5947	8.1045	1.1955	0.1993 - 5.4666	0.0098 - 18.4656	-11.2027 - 20.405	-7.7015 - 13.3674	0.0526	0.8768	506
Vitract	0.9176	0.3549	0.3549	0.0024	0.7074	0.4985	0	0.1787 - 0.5312	0.0377 - 0.6722	-0.6172 - 1.327	-0.3501 - 1.0599	1.758	0.0412	735

External Reference Ranges for Verrucomicrobiota

Verrucomicrobiota (NCBI 74201) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
XenoGene	0	10000	0	1
PrecisionBiome	0.0003183572262059897	0.8823554515838623	0	0.0001
Thorne (20/80%ile)	50.22	6737	0.005	0.6737
Medivere	60	18000	0.006	1.8
GanzImmun Diagostics	70	24000	0.007	2.4
Lab Teletest	500	50000	0.05	5
Nirvana/CosmosId	600	8500	0.06	0.85
Jason Hawrelak	2000	40000	0.2	4
Jason Hawrelak	20000000	400000000	2000	40000

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Amino Acid and similar	2-hydroxyethyl)trimethylazanium {choline}	1 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar	Epicatechin {Green tea polyphenol}	1 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar	Ethanoic acid {Vinegar}	2 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar	Lycopene {Glucosamine (GS)}	1 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar	N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide {Melatonin}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Antibiotics, Antivirals etc	azithromycin,[CFS]	1 Studies recorded. The consensus is Decreases👶, Click for details.
Antibiotics, Antivirals etc	minocycline [CFS]	1 Studies recorded. The consensus is Increases👶, Click for details.
Common and OTC Supplements	1,4-a-D-glucan branched {Amylopectin}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Common and OTC Supplements	3,3',4',5,7-pentahydroxyflavone {Quercetin}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Common and OTC Supplements	long-term, moderate-intensity exercise {exercise}	1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	Amylum {Starch}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style	dietary fiber	7 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	Fiber, total dietary	7 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	high-fat diets	2 Studies recorded. The consensus is Increases👶👪, Click for details.
Diet Style	High-fibre diet {Whole food diet}	7 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	hypocaloric hyperproteic diet	2 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	ketogenic diet	2 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	low protein diet	1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	Pisum sativum {pea}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style	Slow digestible carbohydrates. {Low Glycemic}	7 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	Traditional Mediterranean diet {Mediterranean diet}	2 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	whole-grain diet	1 Studies recorded. The consensus is Increases👶, Click for details.
Drug or "Non-drug"	Methylene blue	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	2-(3,4-Dihydroxyphenyl)-3,7-dihydroxychromen-4-one {Fisetin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one {Luteolin}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Flavonoids, Polyphenols etc	5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one {Apigenin }	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	Catechol {Catecholamines}	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	Grape Polyphenols {Grape Flavonoids}	3 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	Humulus lupulus compound {Xanthohumol}	3 Studies recorded. The consensus is Decreases👶, Click for details.
Flavonoids, Polyphenols etc	polyphenols	3 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	Pyroguaiac acid {Guaiacol}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Flavonoids, Polyphenols etc	Quercetin-3-O-rutinoside {Rutin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	red wine polyphenols	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	resveratrol-pterostilbene {grapes, blueberries}	1 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	resveratrol-pterostilbene x Quercetin {quercetin x resveratrol}	3 Studies recorded. The consensus is Increases👶, Click for details.
Flavonoids, Polyphenols etc	theabrownin {theabrownin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	A dairy product produced by coagulation of the milk protein casein {Cheese}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Adeps suillus {Lard}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Agaricus bisporus {White button mushrooms}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Aloe vera {True Aloe}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	alpha-linolenic acid {Omega-3}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Aronia arbutifolia,Aronia melanocarpa {Chokeberry}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Astragalus	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Avena sativa x Hordeum vulgare {barley,oat}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Bovine Milk Products {Dairy}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Caffeine	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Capsicum annuum {Peppers} {Cayenne Pepper, Hot Pepper}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Coffee	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Cola aspartame {Diet Cola}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	eicosapentaenoic acid (EPA),docosahexaenoic acid (DHA) {Fish Oil}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Eucalyptus {Gum Tree}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Fagopyrum esculentum {Buckwheat}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Far Infrared Therapy {Far infrared Sauna }	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	fat	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Fragaria × ananassa {Strawberry}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	fruit	7 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	fruit/legume fibre	7 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	grapes	3 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	henopodium quinoa {Quinoa}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Hordeum vulgare {Barley}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Humulus lupulus {Hops}	3 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Hydrastis canadensis {Goldenseal}	4 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Ipomoea batata {Purple sweet potatoes}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	laminaria digitata {Oarweed}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Lycium barbarum x Lycium chinense, {Goji Fruit, Juice}	2 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Malus domestica {apple}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	olive oil {olive oil}	2 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Punica granatum {pomegranate}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	red wine	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	refined wheat breads	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Salvia hispanica {Chia Seeds}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	soy	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Taraxacum officinale {Dandelion}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	tea	2 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	tomato powder	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Vaccinium vitis-idaea {lingonberries}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Zea mays {maize}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine}	4 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	allium sativum {garlic}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Ayurvedic herbal formula {Triphala}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Crataegus {Hawthorn}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Diferuloylmethane {Curcumin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	fucoidan {Brown Algae Extract}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Monascus purpureus x Oryza sativa {Red yeast rice}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Trigonella foenum-graecum {Fenugreek}	3 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Vanillin {Vanilla}	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	Zingiber officinale Roscoe {ginger}	1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items	bismuth subsalicylate {Pepto-Bismol}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Miscellaneous, food additives, and other odd items	Polyethylene glycol {PEG}	2 Studies recorded. The consensus is Increases👶👪, Click for details.
Miscellaneous, food additives, and other odd items	Sleep apnea {partial sleep deprivation}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Not Classified	Nitrogen Oxide x Particulate Matter {Urban air pollutant}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar	(2->1)-beta-D-fructofuranan {Inulin}	4 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	fructo-oligosaccharides	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	High-amylose maize starch {HAMS}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar	oligosaccharides {oligosaccharides}	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	Plantago {Psyllium}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar	resistant starch	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	ß-glucan {Beta-Glucan}	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	xylooligosaccharide	1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other	Entyvio {Vedolizumab}	1 Studies recorded. The consensus is Increases👶, Click for details.
Prescription - Other	fenbendazole,(prescription)	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Akkermansia muciniphila {Pendulum Probiotic}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	bacillus	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	bacillus subtilis {B.Subtilis }	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	bacillus,lactobacillus,streptococcus,saccharomyces probiotic	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Enterococcus faecium sf 68 {bioflorin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Heyndrickxia coagulans {B. coagulans}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Lacticaseibacillus casei {L. casei}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Lacticaseibacillus rhamnosus {l. rhamnosus}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	lactobacillus acidophilus {L. acidophilus}	1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics	lactobacillus helveticus,lactobacillus rhamnosus	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Lactobacillus mucosae	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Lactobacillus plantarum {L. plantarum}	2 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Saccharomyces cerevisiae var boulardii {S. boulardii}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Sugar and similar	d-galactose {milk sugar}	1 Studies recorded. The consensus is Increases👶, Click for details.
Sugar and similar	ß-(1?4)-linked D-glucosamine and N-acetyl-D-glucosamine {Chitosan}	1 Studies recorded. The consensus is Increases👶, Click for details.
Sugar and similar	synthetic disaccharide derivative of lactose {Lactulose}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Ferrum {Iron Supplements}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	folate {Vitamin B9}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Mixture of Vitamin B? {B Vitamins}	3 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Riboflavin {Vitamin B2}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Selenomethionine {Selenium supplement}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Silver nanoparticles {Colloidal silver}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	vitamin d	2 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Zinc {Zinc Supplements}	4 Studies recorded. The consensus is Increases👶, Click for details.