Clostridium perfringens: NCBI 1502, [species]

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| "Bacillus perfringens" Veillon and Zuber 1898| "Bacterium welchii" Migula 1900| 'Clostridium plagarum'| ATCC 13124| Bacillus perfringens| Bacterium welchii| BCRC 10913| CCRC 10913| CCRC:10913| CCUG 1795| CIP 103409| Clostridium perfringens| Clostridium perfringens (Veillon and Zuber 1898) Hauduroy et al. 1937| Clostridium plagarum| Clostridium sp. NCIM 2677| DSM 756| JCM 1290| LMG 11264| LMG:11264| NCAIM B.01417| NCCB 89165| NCIMB 6125| NCTC 8237

1. Food Poisoning:

   • Clostridium perfringens is a common cause of foodborne illness. Consuming food contaminated with large numbers of C. perfringens spores, which then germinate and produce toxins in the intestines, can lead to symptoms such as abdominal cramping and diarrhea. This type of food poisoning is often associated with improperly cooked or stored meats.

2. Gas Gangrene:

   • In addition to food poisoning, certain strains of C. perfringens can cause serious infections, including gas gangrene. Gas gangrene is a rapidly progressing, life-threatening condition characterized by the production of gas within tissues. It is often associated with trauma or injury that introduces C. perfringens into deep tissues.

3. Necrotizing Enteritis:

   • C. perfringens has been implicated in cases of necrotizing enteritis, an inflammation of the small intestine that can lead to tissue damage. This condition is more commonly associated with strains producing the enterotoxin CPE (Clostridium perfringens enterotoxin).

4. Type A Strains:

   • Most human infections are caused by C. perfringens Type A strains. These strains can produce various toxins, including alpha toxin, which plays a role in gas gangrene, and enterotoxin, which is responsible for food poisoning.

5. Antibiotic-Associated Diarrhea:

   • In some cases, C. perfringens can be involved in antibiotic-associated diarrhea. Disruption of the normal intestinal microbiota by antibiotics may allow C. perfringens to proliferate and cause diarrhea.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Clostridium perfringens impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.41869014501571655	0.6282524466514587	Gottschalkia acidurici	Parent Taxa
0.3342342674732208	0.5299264192581177	Kluyvera sp. CRP	Parent Taxa
0.30900171399116516	0.5943343639373779	Aeromonas veronii	Parent Taxa
0.2982833981513977	0.5760455131530762	Coprococcus catus	Parent Taxa
0.2895406484603882	0.4940061569213867	Clostridium gelidum	Parent Taxa
0.2675984501838684	0.5484899282455444	Coprococcus comes	Parent Taxa
0.2622699737548828	0.5381079316139221	Dorea formicigenerans	Parent Taxa
0.26024144887924194	0.5243511199951172	Wansuia hejianensis	Parent Taxa
0.25997820496559143	0.5393837094306946	[Ruminococcus] torques	Parent Taxa
0.25245344638824463	0.5328859090805054	Blautia obeum	Parent Taxa
0.2522978186607361	0.5093643069267273	Bifidobacterium eulemuris	Parent Taxa

Other bacteria of the same rank impacting Clostridium perfringens

R2	Slope	Tax Name	Parent Chart